Tokyo Tech, School and Graduate School of Bioscience and Biotechnology

Research & Education

Joint-Use Facilities

Center for Biological Resources and Informatics

The Center for Biological Resources and Informatics (Biocenter) was established as a joint-use facility in 2003 based on Gene Research Center (established in 1989), Research Center for Experimental Biology (established in 1994), and Radioisotope Research Center (established in 2001); but in 2011 the center was reorganized again and the Radioisotope Division was separated as Radiation Research and Management Center. The renewed Bio-center consists of Support Division (Section of Gene Experiment and Section of Experimental Biology) and Research Division (Section of Protein Informatics, Section of Genome Informatics, and Section of RNA Informatics). Support Division provides (i) education, training and safety management in the handling of recombinant DNA and experimental animals, (ii) advanced instruments and spaces for recombinant DNA technology and animal experiments, and (iii) maintenance service for laboratory animals and plants. The mission of research division is to carry out leading bioinformatics research on protein, DNA, and RNA in the post sequence era.

Center for Biological Resources and Information

Support Division

Section of Gene Experiment
Associate Prof. Shinji Masuda
Stress sensing mechanisms of photosynthetic organisms
Assistant Prof. Mie SHIMOJIMA
Plant signaling network mediated by membrane lipid-derived signaling molecules
Section of Experimental Biology
Assistant Prof.  Junji HIROTA
Molecular mechanisms of development of the olfactory system

Research Division

Section of Protein Informatics
Professor  Minoru SAKURAI
Bioinformatics of the structure-function relationship of proteins
Assistant Prof. Tadaomi FURUTA
Computational biophysics study of protein structure, function, and dynamics
Assistant Prof.  Kazunori TACHIBANA
Cell and developmental biology of marine inverte brates and starfish genome project
Section of Genome Informatics
Professor  Hiroyuki OHTA
Elucidation of chloroplast function and evolution with comparative genomics and transcriptomics
Section of RNA Informatics
Professor  Takashi GOJOBORI
Associate Prof.  Yasunori AIZAWA
Retrotransposon, DNA methylation, Human intergenic RNA, intrinsically disordered protein, Signal transduction
バイオセンター研究内容図1
バイオセンター研究内容図
Light-dependent biofilm formation (right) of the purple bacterium R. palustris (left)
バイオセンター研究内容図
Imaging of the mouse olfactory system using gene-targeting (left) and fluorescent probe (right) techniques
バイオセンター研究内容図
The three dimensional structure of photoactive yellow protein (left) and its molecular motion (right)
バイオセンター研究内容図
Pronuclear fusion process (upper) progresses in parallel with the first embryonic cell cycle (lower) in starfish.
バイオセンター研究内容図

Endowed Research Section

Dainichiseika-Donated Chair of Research Division for Innovative Biomaterials
Associate Prof. Norihiko ITO
Regenerative medicine, Alternatives to animal testing
Assistant Prof. Takayuki ENOMOTO
Cell differentiation, Transcription factor, Epigeneitics, Sensory system
Assistant Prof. Wataru TSUKIMURA
Application to biomaterials by natural and synthetic matrix