研究成果

【代表論文・総説】

相澤研発足後の研究成果

  • [1] Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein.
    Fukuda, M and Aizawa, Y.
    Genes to Cells, in print.
  • [2] リボゾームプロファイリング時代のRNAノンコーディング性の評価
    北野翔平、福田牧葉、相澤康則
    細胞工学 Vol. 34 (2015)
  • [3] Polymorphic L1 retrotransposons are frequently in strong linkage disequilibrium with neighboring SNPs.
    Higashino S, Ohno T, Ishiguro K, Aizawa Y.
    Gene, 541(1), 55-9 (2014).
  • [4] A peptide nucleic acid (PNA) heteroduplex probe containing an inosine-cytosine base pair discriminates a single-nucleotide difference in RNA.
    Matsumoto K, Nakata E, Tamura T, Saito I, Aizawa Y, Morii, T.
    Chemitstry 19, 5034-40 (2013)
  • [5] Genes that Integrate multiple adipogenic signaling pathways in human mesenchymal stem cells.
    Ito T, Tsuruta S, Tomita K, Kikuchi K, Yokoi T, Aizawa Y. Biochem. Biophys. Res. Commun. 409(4), 786-91 (2011)
  • [6] Basic and clinical studies on functional RNA molecules for advanced medical technologies.
    Takizawa T, Gemma A, Ui-Tei K, Aizawa Y, Sadovsky Y, Robinson JM, Seile M, Miyake K. J. Nippon Med. Sch., 77(2), 71-9 (2010)
  • [7] Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation.
    Kikuchi K, Fukuda M, Ito T, Inoue M, Yokoi T, Chiku S, Mitsuyama T, Asai K, Hirose T, Aizawa Y.Nucleic Acids Res., 37(15), 4987-5000 (2009)

独立以前の発表論文

  • [1] Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution.
    Wheelan SJ*, Aizawa Y*, Han JS, Boeke JD.
    Genome Res., 15, 1073-8, (2005) * These authors contributed equally to this work.
  • [2] Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1.
    Hirata A, Ueno M, Aizawa Y, Ohkubo K, Morii T, Yoshikawa S.
    Bioorg. Med. Chem., 13, 3107-16, (2005)
  • [3] The pathway for DNA recognition and RNA integration by a group II intron retrotransposon.
    Aizawa Y, Xiang Q, Lambowitz AM, Pyle AM. Molecular Cell, 11, 795-805, (2003)
  • [4] A general strategy to determine a target DNA sequence of a short peptide: application to a d-peptide.
    Morii T, Tanaka T, Sato S, Hagihara M, Aizawa Y, Makino K.
    J. Am. Chem. Soc., 124, 180-1, (2002)
  • [5] Stability of the dimerization domain effects the cooperative DNA binding of short peptides.
    Aizawa Y, Sugiura Y, Ueno M, Mori Y, Imoto K, Makino K, Morii T. Biochemistry. 38, 4008-17 (1999)
  • [6] Comparison of the sequence-selective DNA binding by peptide dimers with covalent and noncovalent dimerization domains.
    Aizawa Y, Sugiura Y, Morii T. Biochemistry. 38, 1626-32 (1999)
  • [7] Cooperative oligomerization enhances sequence-selective DNA binding by a short peptide
    Morii T, Yamane J, Aizawa Y, Makino K, Sugiura Y.
    J. Am. Chem. Soc., 118, 10011-10017 (1996)
  • [8] RNA cleavage by C-1027 chromophore, an enediyne antitumor antibiotic: high selectivity to an anticodon arm.
    Totsuka R, Aizawa Y, Uesugi M, Okuno Y, Matsumoto T, Sugiura Y. Biochem. Biophys. Res. Commun., 208(1), 168-73, 1995.

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