研究成果

【代表論文】

  • [1] Yano K, Wachi M, Tsuchida S, Kitazume T, Iwai N. (2015). Degradation of benzotrifluoride via the dioxygenase pathway in Rhodococcus sp. 065240. Biosci. Biotechnol. Biochem., 79:496-504.
  • [2] Uchida M, Hirasawa T, Wachi M. (2014). Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation. Arch. Microbiol., 196:871-879.
  • [3] Matsuda Y, Itaya H, Kitahara Y, Theresia NM, Kutukova EA, Yomantas YA, Date M, Kikuchi Y, Wachi M. (2014). Double mutation of cell wall proteins CspB and PBP1a increases secretion of the antibody Fab fragment from Corynebacterium glutamicum. Microb. Cell Fact., 13:56.
  • [4] Maeda T, Wachi M. (2013). 3' Untranslated region-dependent degradation of the aceA mRNA, encoding the glyoxylate cycle enzyme isocitrate lyase, by RNase E/G in Corynebacterium glutamicum. Appl. Environ. Microbiol., 78:8753-8761.
  • [5] Heinemann IU, Schulz C, Schubert WD, Heinz DW, Wang YG, Kobayashi Y, Awa Y, Wachi M, Jahn D, Jahn M. (2010). Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin. Antimicrob. Agents Chemother., 54:267-272.
  • [6] Tatsumi R, Wachi M. (2008). TolC-dependent exclusion of porphyrins in Escherichia coli. J. Bacteriol., 190:6228-6233.
  • [7] Nakamura J, Hirano S, Ito H, Wachi M. (2007). Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production. Appl. Environ. Microbiol., 73:4491-4498.
  • [8] Kruse T, Blagoev B, Løbner-Olesen A, Wachi M, Sasaki K, Iwai N, Mann M, Gerdes K. (2006). Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli. Genes Dev., 20:113-124.
  • [9] Awa Y, Iwai N, Ueda T, Suzuki K, Asano S, Yamagishi J, Nagai K, Wachi M. (2005). Isolation of a new antibiotic, alaremycin, structurally related to 5-aminolevulinic acid from Streptomyces sp. A012304. Biosci. Biotechnol. Biochem., 69:1721-1725.
  • [10] Takada A, Nagai K, Wachi M. (2005). A decreased level of FtsZ is responsible for inviability of RNase E-deficient cells. Genes Cells, 10:733-741.
  • [11] Gitai Z, Dye NA, Reisenauer A, Wachi M, Shapiro L. (2005). MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell, 120:329-341.
  • [12] Iwai N, Nagai K, Wachi M. (2002). Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci. Biotechnol. Biochem., 66:2658-2662.

【主な日本語総説】

  • [1] 川崎寿、和地正明 (2012). Corynebacterium glutamicumのグルタミン酸排出チャネルの発見とその有用物質生産への展開、化学と生物、50:441-449.
  • [2] 和地正明 (2010). 大腸菌RNase Gによる解糖系の制御、バイオサイエンスとインダストリー、68:34-38.
  • [3] 中村純、和地正明 (2008). Corynebacterium glutamicumによるグルタミン酸発酵生産のメカニズム、Food & Food Ingredients Journal of Japan. 213:1103-1109.

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