研究成果

【代表論文】

  • [1] Asymmetric synthesis of 12-hydroxyheptadecatrienoic acid and its 5,6-dihydro- and 14,15-dehydro-derivatives. Y. Kobayashi, M. Morita, N. Ogawa, D. Kondo, T. Tojo, Org. Biomol. Chem. 2016, 14, 10667–10673.
  • [2] Synthesis of (–)-piperitylmagnolol featuring ortho-selective deiodination and Pd-catalyzed allylation. A. Ikoma, N. Ogawa, D. Kondo, H. Kawada, Y. Kobayashi, Org. Lett. 2016, 18, 2074–2077.
    佐藤ジャーナル賞受賞
  • [3] Metal catalyst-free substitution of allylic and propargylic phosphates with diarylmethyl anions. H. Kawashima, N. Ogawa, R. Saeki, Y. Kobayashi, Chem. Commun. 2016, 52, 4918–4921.
    佐藤ジャーナル賞受賞
  • [4] Activation of marginally reactive boron enolates by MeLi for the formation of enol phosphates and synthesis of the Δ9-THC intermediate. H. Kawada, A. Ikoma, N. Ogawa, Y. Kobayashi, J. Org. Chem. 2015, 80, 9192–9199.
  • [5] Synthesis of (–)-mesembrine using the quaternary carbon-constructing allylic substitution. T. Ozaki, Y. Kobayashi, Org. Chem. Front. 2015, 2, 328–335.
  • [6] Synthesis of the PMB ether of 5,6-epoxyisoprostane E2 through aldol reaction of the α-bromocyclopentanone. H. Kawashima, Y. Kobayashi, Org. Lett. 2014, 16, 2598–2601.
    佐藤ジャーナル賞受賞
  • [7] Synthesis of maresin 1 and (7S)-isomer. N. Ogawa, T. Tojo, Y. Kobayashi, Tetrahedron Lett. 2014, 55, 2738–2741.
  • [8] Synthesis of trans-2,6-disubstituted cyclohexanones through allylic substitution. Y. Kobayashi, C. Feng, A. Ikoma, N. Ogawa, T. Hirotsu, Org. Lett. 2014, 16, 760–763.
    佐藤ジャーナル賞受賞, Selected by Synfacts 2014, 10(5), 0519
  • [9] Synthesis of cyclobakuchiols A, B, and C using conformation-controlled stereoselective reactions. H. Kawashima, Y. Kaneko, M. Sakai, Y. Kobayashi, Chem. Eur. J. 2014, 20, 272–278.
  • [10] Allylic substitution for construction of a chiral quaternary carbon possessing an aryl group. C. Feng, Y. Kobayashi, J. Org. Chem. 2013, 78, 3755–3766.
  • [11] Synthesis of the amino acid conjugates of epi-jasmonic acid. N. Ogawa, Y. Kobayashi, Amino Acids, 2012, 42, 1955–1966.
  • [12] Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. L. B. Sheard, X. Tan, H. Mao, J. Withers, G. Ben-Nissan, T. R. Hinds, Y. Kobayashi, F.-F. Hsu, M. Sharon, J. Browse, S. Y. He, J. Rizo, G. A. Howe, N. Zheng, Nature, 2010, 468, 400–405.

【主な日本語総説】

  • [1] ピコリン酸基を脱離基とするアリル化反応の開発と有機合成への応用
    小林雄一, 有合化, 2016, 印刷中.
  • [2] シクロペンタ-4-エン-1,3-ジオールのモノエステルを活用したシクロペンタノイド合成法の開発と応用
    小林雄一, 有合化, 2011, 69, 680–690.

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